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controlled clinical trials involving protonix 10-, 20-, or 40-mg doses for up to 12 months, the following adverse events considered by investigators to be possibly, probably, or definitely related to drug occurred in 1 or more of gerd patients on long-term therapy.

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in this multicenter, pharmacodynamic crossover study, a 40 mg oral dose of protonix for delayed-release oral suspension administered in a teaspoonful of applesauce was compared with a 40 mg oral dose of protonix delayed- release tablets after administration of each formulation once daily for 7 days.

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as demonstrated in table 9, protonix 40 mg and 20 mg were significantly superior to ranitidine at every timepoint with respect to the maintenance of healing.

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you should tell your doctor before you take protonix if you have osteopenia, which is low bone mineral density, or osteoporosis.

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in short-term us clinical trials, erosive esophagitis healing rates in the 107 elderly patients 65 years old treated with protonix were similar to those found in patients under the age of 65.


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